Destruction of Microorganisms The destruction of microorganisms is critical in various fields, including healthcare, food industry, and environmental control, to prevent infections, spoilage, and contamination. This process is achieved through physical, chemical, and biological methods, depending on the level of microbial control required. Levels of Microbial Control Physical Methods of Microbial Destruction 1. Heat 2. Filtration 3. Radiation 4. Desiccation 5. Low Temperatures Chemical Methods of Microbial Destruction 1. Alcohols