CHN – II – DRUGS. Paracetamol dose250,500, 650 mg1 gm in adults. Route :- Oral, I.V, I.M & I.V Infusion group – Antipyretic-a Analgesic brand name Panadol-Panadol Calpol-Calpol Tylenol Alvedon-Alvedon Mode of Action- Paracetamol inhibits the synthesis of prostaglandin which is reduced by the active forms cox 1 and cox 2.It exerts central anaesthetic effects through activation of the descending cerato-nergic pathway. Indication of paracetamol-FeverHead ache-head oneTensionMigraine-migrainebackacheMuscle pain Toothache-Muscle pain