UNIT 10 Comfort, Rest & Sleep and Pain Patient Comfort. Definition of Patient Comfort Patient comfort refers to a state of physical, emotional, psychological, and spiritual well-being that promotes relaxation, relief from distress, and overall ease during healthcare experiences. Comfort is a fundamental nursing goal and an essential aspect of holistic care. Types of Comfort in Nursing Factors Affecting Patient Comfort Principles of Comfort in Nursing Nursing Interventions to Promote