UNIT 5 Acid base maintenance. Acid-Base Maintenance: Introduction Acid-base balance refers to the regulation of hydrogen ion (H⁺) concentration in the body to maintain the normal pH of blood and tissues. The body’s pH is maintained between 7.35 and 7.45, which is essential for enzymatic functions, cellular activities, and overall homeostasis. 1. pH and Its Significance in Biochemistry 2. Buffer Systems for Acid-Base Regulation The body uses buffer systems to