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Functions of the Skin The skin, also known as the integumentary system, is the largest organ of the body. It serves multiple essential functions, ranging from protection to thermoregulation. Here’s an overview of its key functions: 1. Protection 2. Regulation of Body Temperature (Thermoregulation) 3. Sensory Function 4. Excretion 5. Synthesis of Vitamin D 6. Immunological Defense 7. Storage 8. Communication 9. Wound Healing and Regeneration 10. Prevention of Dehydration