🏹 Paracetamol
dose
250,500, 650 mg
1 gm in adults.
Route :– Oral, I.V, I.M & I.V Infusion
group – group
Antipyretic AND Analgesic
brand name
Panadol-Panadol
Calpol-Calpol
Tylenol
Alvedon-Alvedon
Mode of Action-Mode of Action
Paracetamol inhibits the synthesis of prostaglandins which are reduced by the active forms cox 1 and cox 2.
It exerts central anesthetic effects through activation of the descending serotonergic pathway and reduce the body temperature.
Indication of paracetamol–
Contraindication of paracetamol–
🏹 Famotidine – Famotidine (FMT)
group : Histamine H2 receptor antagonist or H2 blocker (antacid).
dose – 20 mg, 40 mg
Route:-Oral
Mode of Action- Famotidine reduces gastric acid production and suppresses pepsin content and acid concentration.
Reduces the volume of HCL and blocks the H2 receptor.
brand name–
Pepsid and Zantac-Pepsid and Zantac
Indications of Famotidine
Hypersensitivity-Hyper sensitivity
Cross-sensitivity TVT of H2 RAS- Cross-sensitivity TVT of H2 RAS
Side effects–
Nursing Responsibility–
🏹 Dicyclomine tablet
Group :-
Dose
Synonyms
MOA (Mode of Action)
Use
Indications
Side effects-Side effects
Nursing Responsibility–
Levocitrizine
group Second generation antihistamines
Route Oral
Dosage
indication :Seasonal allergic rhinitis, rhinitis due to other causes, chronic idiopathic urticaria,
To relieve allergic symptoms like fever, itching, hives.
contraindications: Hypersensitivity,
Severe renal impairment, alcohol use, hemodialysis.
side effects
nursing responsibility
🏹 Ascorbic acid tablet (vitamin c) –
Group – group
Vitamin supplements.
DOSAGE
500 mg
Route
Oral (by mouth), I.M
Use
Side effects-Side effects
Nursing Responsibility–
Check nurse doctor’s order.
🏹 Metronidazole –
Dose -dose
250,400,500,750mg orally.
500 mg /100ml
IV infusion-Iv infusion
Group– group
Antibiotics. Nitroimidazole Antimicrobial..
brand name
Metrozil and Flagile
Mode of Action-Mode of Action
Metronidazole diffuses the organism. By interacting with its DNA, it inhibits the synthesis of proteins, due to which the helical DNA structure is lost and breaks down. So the cells of the susceptible organism are dead.
Side effects-Side effects
Disney Heart Burn
Weight loss Sleep problems
Stomach cramps headache
Nausea, Vomiting Loss of appetite
_Constipation
Indication of metronidazole-Indication of metronidazole
Diarrhea Intestinal amoebiasis
Liver m amoebiasis Bacterial septicemia
Bone and joint infection Meningitis
Brain abscess Skin infection
Mouth infection Dental abscess
Gums infection Bacterial vaginosis
Abdominal infection Lower respiratory tract infection
_Surgical Profile Axis, Colorectal Surgery
Contraindication of metronidazole.
Hypersensitivity First Trimester Pregnancy
Alcoholic patient hepatic in cephalopathy
CNS problem kidney disorder
Nursing Responsibility-Nursing Responsibility
Assess patient for infection before and during treatment.
Monitor the patient’s daily weight, patient status, weakness, and seizures.
🏹 Calcium gluconate tablet –
Group Calcium salt, cardio protective agent
Route – Route
Oral, IV (Intra-Venous)
Dose
Adult:- 500 mg/day
MOA (Mode of Action)
Calcium gluconate increases blood calcium levels or combines with excess potassium and magnesium and results in elevated calcium levels.
Uses
Indications.
hypocalcemia,
cardiac rest
Hyper magnesium
hyperkalemia,
Toxicity of magnesium sulfate, breast feeding, pregnancy.
Contraindications –
Side effect
CV (Cardio Vascular) –
GI (Gastro Intestinal) –
GU (Genitourinary)–
Nursing responsibility –
🏹 Iron & Folic acid tablet –
Group As a supplementary nutrient.
Dose – dose
Route – Route
Can be given orally.
MOA :- Mode of action MOA :– Increases the production of RBC (Red Blood Cell) and HB i.e. Hemoglobin in the body.
Uses
Indications-
Contraindication –
Side effects –
Nursing Responsibility–
Before giving this medicine to the patient, the nurse went to check the five R’s which are Right Patient, Right Time and Right Drug, Right Route, Right Dose etc.
The nurse should check or take a history of any patient for hypersensitivity to this tablet.
Patients should do blood test regularly as per doctor’s instructions so that HB and RBC (Red Blood Cell) count can be checked and treatment can be given to the patient accordingly.
Check whether the patient is constipated or not.
Nurses should not give more than 1mg (milligrams) of folic acid because too much folic acid can cause seizures, which is a side effect of too much folic acid.
In addition, the nurse advises the patient to take an iron tablet before a meal, which increases iron absorption, which is more effective.
Keep checking the patient’s bowel movement so that constipation problem can be detected early.
Do not give folic acid if the patient has pernicious anemia because pernicious anemia is caused by vitamin B12 deficiency.
Also taking iron tablets with citrus fruits or vitamin C increases its absorption.
And iron tablets should not be taken with coffee, tea and dairy products and eggs etc. This nurse advises the patient.
In addition, if any other side effect is observed in the patient, the doctor should be informed immediately.
To check the HB count by reporting the blood to the patient at appropriate intervals and give the dose of this tablet to the patient based on that.
And to ensure that the patient takes the medicine at the right time or not.
🏹 ATENOLOL
Group – group
Anti-hypertensive drug
Antiadrenergic agent
Beta adrenergic blocker
Dosage
Adult :
Initially 50 mg once daily (alone or with diuretic)
May then be increased to 100 mg daily (doses above 100 mg are not beneficial)
In case of Angina, 50 mg daily initially, 100 mg after one week if no response. A maximum of 200 mg can be given daily.
Children:
1.0 – 1.3 mg / kg / 24 hrs once a day.
Mode of action
Atenolol alters the body’s response to nerve impulses, including the heart.
This drug binds to the Beta-1 adrenergic receptor found in vascular smooth muscles and blocks the positive inotropic and chronotropic actions of the heart’s endogenous catecholamines (eg; isoproterenol, norepinephrine & epinephrine).
Indication
Contraindication
Side effects
LABETALOL–
Group
Dosage
Route – IV
Mode of action
INDICATION
Contraindication
Side effects
NIFEDIPINE-
Group
Dosage
Route :- Oral, Sub Lingual
Mode of action
During the depolarization phase of that smooth muscle, calcium iron fluxes through voltage-gated channels.
Nifedipine inhibits the entry of calcium ions by blocking these voltage-dependent L-type calcium channels in vascular smooth muscles and myocardial cells.
It causes coronary vasodilatation and increases coronary blood flow. It reduces total peripheral vascular resistance and also reduces systolic and diastolic blood pressure.
Indication
Contraindication
Assessment
Checking patient’s vital signs (temperature, pulse, respiration and blood pressure), heart rate and health status before and after drug administration.
Patient Education-Patient Education
Giving complete information to the patient about the purpose, side effect, dosage of the medication.
monitoring-monitoring
Keep checking vitals and observe for side effects
Patient history
Taking a thorough history of the patient’s medical history, allergies, blood pressure, heart failure or liver problems. It affects the effect of the drug.
5R – Right Patient, Right Route, Right Dose, Right Time, Right Drug while giving drug to the patient.
Lifestyle counselling
Advise the patient about lifestyle modifications such as exercise. Explain the factors that increase the effect of medicine.
Recording and reporting-Recording and reporting
It is very important to do documentation after the administration of the drug, besides informing the health care team if there are any side effects or changes.
ondansetron
group
Ntematic-Ntematic
(selective serotonin 5-HT3 receptor antagonist)
dose
4mg iv
4mg,8mg oral route
For Adults-For Adults
Maximum dose: 24 mg daily.
Mode of Action- Blocks the action of serotonin. Blocks serotonin 5-HT3 receptor antagonists.
Side effects–
Head one
Constipation
Fatigue
Dizziness
Drowsiness
Allergic reaction-allergic reaction
Irregular heart beat-Irregular heart beat
Serotonin syndrome-serotonin syndrome
Stomach pen-stomach pen
Muscle spasm
Blurred vision-Blurred vision
agitation-agitation
Indication
Nozia
Vomiting
Chemotherapy-chemotherapy
Radiation therapy-Radiation therapy
Surgery
In pregnancy
Contra indication-
Hypersensitivity-Hyper sensitivity
While taking apomorphine.
Myasthenia gravis.-Myasthenia gravis.
-Nursing Responsibility
Assess medical history for allergies. To monitor vital signs
_ Educating the patient about the side effects, purpose, benefits etc. of the medicine
Mannitol
Mannitol is a poly hydroxy aliphatic alcohol.
dose
O.5 -1g/kg 10-20% solution
Infusion rate: 3g/min. Not more than
0.25 to 1.5 g/kg iv bolus injection.
50 to 200gm /24hr iv.
group –
Osmotic diuretic Osmotic diuretic
Mode of Action- Mode of Action
Inhibits water reabsorption in the proximal convoluted tubule and thins the collecting duct and loop of Henle. Increases urine volume. Intracellular water in the brain moves out of cells and into the blood stream. So that extra water comes out of the skull.
Side effects-Side effects
Electrolyte im balance
Dehydration
Fluid overload increases the frequency of urination
Pulmonary edema Congestive heart failure Allergic reaction Confusion
Diarrhea
Caesar
Loss of appetite and increased thirst.
Indication
In cerebral ED
Acute Kidney Dysfunction
Intraocular pressure reduction
Diagnosis of renal function
Glaucoma-Glaucoma
Contraindications
Mannitol Hypersensitivity
Progressive heart failure-Progressive heart failure
Severe dehydration-severe dehydration
Intracranial bleeding
Pulmonary edema
Severe pulmonary congestion-severe pulmonary congestion
Anuria (due to renal disease)
Severe renal dysfunction
Nursing Responsibility-Nursing Responsibility
Regular assessment of fluid balance, renal function and vital signs. Monitoring urine output, electrolyte levels, dehydration etc.
Educating the patient about the side effects, benefits, purpose etc. of mannitol. Give as per proper dose.
Documentation in detail. _iv Site care. Monitor for allergic reactions.
Azithromycin –
Group:
Macrolide antibiotics
dose
Oral route: Adult: 500 to 2000mg once a day
Children: 5-10 mg/kg/day for 3 days.
Mode of Action-Mode of Action
Azithromycin inhibits bacterial protein synthesis, pro-inflammatory cytokine production, neutrophil infestation, and ultration of macrophage polarization.
Side effects-Side effects
Nozia Nozia
Vomiting – Vomiting
Diarrhea
abdominal pan
headache
Dizziness
Skin Recess-Skin Recess
Liver problem-Liver problem
Allergic reaction-allergic reaction
Indication
Bacterial infection
Pneumonia
Bronchitis-bronchitis
Skin and soft tissue infections
Sexually transmitted infection
including chlamydia and gonorrhea
Ear infection-ear infection
sinusitis
Contraindications
Hypersensitivity
Liver disease-liver disease
Irregular heart beat (arrhythmia)
Nursing Responsibility-Nursing Responsibility
Instruct the patient not to take Azithromycin with antacid food. Advise the use of protective clothing and sunscreen to prevent photosensitivity reactions.
_To monitor for allergies or any side effects including gastrointestinal issues etc. after administration of Ed.
Diazepam Diazepam
Dosage: 10-30mg/daily
Group: Benzodiazepam
indication
Anxiety
Caesar
Insomnia
Muscle Spas-Muscle Spas
reduce the symptoms of alcohol
Rest less in funt we are ventilated.
Cerebral palsy
Pre medicate before surgery.
Contra indication-Contra indication
Myasthenia gravis-myasthenia gravis
Severity recipe rate tree in sufficiency
Severe hepatic insufficiency
Sleep apnea syndrome
A cute narrow angle glaucoma
Mechanism of action-mechanism of action
Dije palm binds to the receptors of the spinal cord and brain and inhibits the effect of gamma amino butyric acid in it, so it works as a sedative, anxiolytic, muscle relaxant, anticonvulsant.
Side effects-Side effects
Droozyness
Fatigue
Ataxia
to venous thrombosis
Depression
Confusion-Confusion
A headache
Hypo activity
Slurred speech-slurred speech
Syncope
Tremor-tremor
Cardiovascular collapse
Blurred vision-Blurred vision
Nystagmus-Nystagmus
Nursing Interventions-Nursing Interventions
Assessment:
Thorough assessment of medical history, allergies, current medications of patients receiving diazepam.
Whiter signs specifically monitor respiration rate, heart rate, and blood pressure.
Education:-Education:
Educate the patient about the side effects, purpose of diazepam.
Administration:– Administration:
Administer dosage as per proper prescription, guidelines.
Monitor for adverse reactions to this drug during and after administration.
Safety Major:-Safety Major:
Keep the side rail of the bed up as there is a chance of the patient falling down due to the sedative effect.
Avoiding the activity
Providing a proper environment as seizures can cause photophobia.
Respiratory monitor-Respiratory monitor
Observe respiratory status especially when patient has respiratory related problem as diazepam relaxes muscles.
Cesarean Precaution:
To prevent injury by inappropriate major during seizures when using drug as an anti-colorant to the patient.
Monitoring for AdWords Effect:-Monitoring for AdWords Effect:
Regularly assess drug toxicity.
Drug toxicity CT like excessive sedation, confusion, respiratory depression
Patient Communication:-Patient Communication:
Open and clear communication with the health care worker if side effects or other problems are observed.
Withrol Precautions:-Withrol Precautions:
Gradually minimize the dose to prevent withdrawal symptoms.
Documentation– Documentation
Proper recording of administration time, patient no response, adverse effect etc.
Alprazolam
Dosage: 0.25-0.5mg/2-3 time/daily
Group: Benzodiazepam
indication
Generalized Anxiety Disorder
Panic disorder
Contra indication – Contra indication
Lung disease – Lung disease
Liver disease-liver disease
Kidney diseases
Pregnancy and breast feeding
Hypersensitivity
My Asthenia Gravis
of the sleep app
Co-administration with key to conazole.
In a cute narrow angle Glocko
Mechanism of action-mechanism of action
Alprazolam depresses the central nervous system by binding to the GABA-A receptor, which decreases the brain’s abnormal excitability.
Side effects Side effects
Drowsiness
Tiredness
Dizziness
Sleep problem
Slurred speech-slurred speech
Trouble concentrating
Nursing Interventions Nursing Interventions
“Sam S Diazepam”
Pregnancy and lactation-pregnancy and lactation
This drug affects the fetus during pregnancy so should be avoided during pregnancy and lactation.
IBUPROFEN
Group
Non steroidal anti inflammatory drug (NSAID – Non steroidal anti inflammatory drug)
Propionic acid derivatives
Dosage – dose
Adult – 400mg 3 times a day (maximum 2.4 g daily).
Children – Mild analgesic or antipyretic : 10-15mg/kg/dose every 4-6 hours.
Mode of action
It inhibits the biosynthesis and release of prostaglandins. This drug inhibits the cyclo-oxygenase enzyme and thus the synthesis of prostaglandins. This compound does not inhibit the formation of leukotrienes that play a role in inflammation.
Indication
Rheumatoid arthritis
Osteoarthrosis
Seronegative arthropathy
Cervical spondylosis
Dental and traumatic inflammation
Primary dysmenorrhea
Contraindication
Active peptic ulcer
Gastrointestinal bleeding
Hypersensitivity
during pregnancy
Side effects
Nozia
Vomiting
Epigastric discomfort
Disneyness
headache
Skin race
Thrombocytopenia
Nursing responsibility
Assessment
Checking patient’s vital signs (temperature, pulse, respiration and blood pressure), heart rate and health status before and after administering drugs.
Patient education
Giving complete information to the patient about the purpose, side effect, dosage of the medication.
monitoring
Keep checking vitals and observe for side effects
Patient history
Taking a complete history of the patient about medical history, allergies, liver problems etc. It affects the effect of the drug.
5R – Right Patient, Right Route, Right Dose, Right Time, Right Drug while giving drug to the patient.
Lifestyle counselling
Advise the patient about lifestyle modifications such as exercise. Explain the factors that increase the effect of medicine.
Recording and reporting
Documentation after administration of the drug is very important, besides informing the health care team if there are any side effects or changes.
Aspirin
Dosage: 50-150mg/daily
Group: Antiplatelet, NSAID Analgesic, Antipyretic
indication
Angina pectoris Angina pectoris
Angina pectoris: prophylactic
Ankylosing spondylitis
Reduction Cardiovascular Risk
Color rectal cancer-Colo rectal cancer
Fever
Is chemical stroke
Ischemic Stroke: Prophylaxis
Myocardial infarction
Myocardial infarction: prophylaxis
Osteoarthritis
Pain
Revascularization Procedures: Prophylaxis
Rheumatoid arthritis-rheumatoid arthritis
Systemic lupus erythematosus
Contra indication-Contra indication
Peptic ulcer-peptic ulcer
Hypersensitivity-hyper sensitivity
Gastritis-Gastritis
Hemophilia
Stomach or intestinal bleeding
Allergy to NSAID
Mechanism of action-mechanism of action
NSAIDs:
As an NSAID, cyclins inhibit the activity of oxygenase, which initiates the inflammatory process by forming prostaglandins.
-Anti Platelet:-Anti Platelet:
Aspirin inhibits the activity of acyl cyclooxygenase-1 to inhibit the synthesis of thromboxane A2, which is responsible for platelet aggregation.
Side effects-Side effects
Abdominal pain-abdominal pain
Bloody or cloudy urine
Change in Consciousness
Constipation
conversion
Decreases frequency or amount of urine
Difficult Brethrig-Difficult Brethrig
Drowsiness
Nursing Interventions
Assessment:
Conduct a thorough assessment of the patient’s medical history, allergies and current medications.
Assessing risk factors of gastrointestinal bleeding or bleeding disorders.
Education:
Providing education about drug’s side effects, purpose.
Taking food and milk with aspirin can reduce the risk of gastrointestinal irritation.
Monitoring:-Monitoring:
Especially blood pressure to monitor vital signs.
To monitor for building signs like easy bruising, bloody stool, prolonged bleeding from cut.
Gastro Intestinal Protection:
Taking a proton pump inhibitor and H2 blocker with aspirin can minimize the risk of GI bleeding, especially in patients with a history of peptic ulcer.
Anti Platelet Effect:-Anti Platelet Effect:
Aspirin works as an anti-platelet so monitor for signs of bleeding.
Regular monitoring of platelet count.
Renal function
Monitor renal function especially if renal problems are present.
Interaction with Other Medications:
Taking other anti-plate agents, anti-coagulants along with this drug increases the risk of bleeding.
Patient compliance:
Advise patient to take dose as per schedule.
Communication:
Communicating with other health care team members to effectively coordinate care.
Encouraging the patient to clear all his queries and doubts.
Documentation: Documentation:
Documenting administration, patient response, and side effects.
To record the progress of the patient’s condition.
🏹 STREPTOKINASE
Group – Thrombolytic medicine
Dosage – dose
Acute myocardial infraction : Intravenous 750,000 – 1.5 million i.u. in 1 hour.
Intracoronary : 20000 i.u. stat and then give 2000 – 4000 i.u./min 30 – 90 min later.
Deep venous & arterial thrombosis: 1.5 million i.u./hr infused over 6 hours.
Not given in children.
Mode of action
It works by forming a complex with plasminogen. which binds loosely to fibrin and converts plasminogen to plasmin. It has no intrinsic activity.
Indication
Acute myocardial infarction
Pulmonary embolism
Deep vein thrombosis
Arterial thrombosis
Acute thrombosis of central retinal vessels
Extensive coronary emboli
-Severe iliofemoral thrombophlebitis
Contraindication
Have undergone surgery in the last 10 days
Severe hypertension
Serious gastrointestinal bleeding
Hemorrhagic disorders
Previous cerebrovascular accident
Side effects
Fever, allergic reaction, bleeding from different sites, anaphylaxis, arrhythmias, Bronchospasm.
Nursing responsibility
Assessment
Checking patient’s vital signs (temperature, pulse, respiration and blood pressure), heart rate and health status before and after drug administration.
Patient Education
Giving complete information to the patient about the purpose, side effect, dosage of the medication.
monitoring
Continue to check vital signs and observe for side effects
Patient history
Taking a thorough history of the patient’s medical history, allergies, blood pressure, heart failure or liver problems. It affects the effect of the drug.
5R – Right Patient, Right Route, Right Dose, Right Time, Right Drug while giving drug to the patient.
Close observation for bleeding while administering streptokinase as this increases the risk of hemorrhage.
Recording and reporting
It is very important to do documentation after the administration of the drug, besides informing the health care team if there are any side effects or changes.
DIGOXIN
Group – Digitalis (cardiac) Glycosides
Mode of action
It acts directly on the heart, increases the force of myocardial contraction, has positive and negative isotopic effects, digoxin reduces heart size, venous pressure and blood volume, causes diuresis, relieves edema.
Dosage – dose
Adult
0.25-1.5mg daily
Maintenance dose : 0.25-0.5mg daily
Children
10-20mcg/kg 6 hourly
Maintenance dose : 10-20mcg/kg daily
Digitalizing dose: IM or IV; 10mcg/kg
Indication
Congestive cardiac failure
Cardiac dysrhythmias
paroxysmal supraventricular
Tachycardia
Contraindication
Hypersensitivity
Ventricular fibrillation
Ventricular tachycardia
Hypertrophic obstructive cardiomyopathy
Hyperkalemia
Hypercalcemia
Kidney dysfunction
Digoxin Toxicity
Nausea
Vomiting
Blurred vision
Confusion
Irregular heartbeat
Nursing responsibility
Perform regular vital sign assessments
Educating patients about side effects, benefits, complications etc. of medicines
Monitor electrolyte balance
Checking proper dosage and prescription
Do the documentation
Ask for regular follow up.
PROMETHAZINE
Group – first generation antihistamine
Route – Oral
dose
Adult
Oral : 25 mg
Usual dose 6.25 – 12.5 mg
IM/IV : 25 mg
in children
Oral : 0.125 – 0.5mg/kg/dose
Maximum dose : 25mg/dose
Mode of action
Promethazine is an antihistamine that acts by blocking histamine receptors, acts as a sedative, and acts on the CNS to induce drusinase and is also an antiemetic.
Indication
Allergic conditions (itching, runny nose)
Motion sickness
Nausea, vomiting
Sedation
Pre-operative, post-operative and obstetric sedation
Contraindication
Hypersensitivity
Coma, liver disease
Breast feeding
Treatment of lower respiratory tract symptoms such as asthma
Children <2 years
Intra-arterial or subcutaneous administration
Side effects
Allergic reaction
Photosensitivity
Hypotension
Extra pyramidal symptoms
Disneyness
Constipation
Urinary retention
Blurred vision
Dry mouth
Sedation
Nursing Responsibility
To follow the 5Rs.
The nurse takes the patient’s medical history, allergies, and current medications.
Administer the dose prescribed by the doctor to the patient.
Educate the patient about the drug including its side effects, complications, etc.
Monitor the patient for side effects.
To monitor vital signs.
Recording and reporting after giving Narsingh drug.
Asking the patient to take safety measures due to the sedative effect of this medicine i.e. asking him not to drive or operate machinery.
Perform respiratory monitoring.
Metformin
group
Anti hyperglycemic agent/antidiabetic.
Belongs to the Bigunaid group.
route
Also available in oral and liquid form.
dosage
adult
IniciL Dose : 250mg
2-3 times/day with meal.
Increase the dose gradually after an interval of two weeks.
Child
It is not applicable.
mode of action
Metformin works primarily by reducing the production of glucose in the liver and increasing the body’s sensitivity to insulin.
It works by activating AMP (activated protein kinase), a key enzyme involved in cellular energy regulation.
This results in decreased production of glucose from the liver and peripheral
Better utilization of glucose by tissues,
It helps in reducing blood sugar levels in people with type 2 diabetes.
indication
type 2 diabetes,
gestational diabetes,
Prevent type 2 diabetes,
Treat and Prevent Polycystic Ovary Syndrome.
contraindications
Hypersensitivity,
Acute or chronic metabolic acidosis, including diabetic ketoacidosis with or without accompanying coma,
Severe renal impairment,
Congestive heart failure,
Severe liver disease.
side effects
Nausea, diarrhea, lactic acidosis, abdominal
Discomfort, loss of appetite, feeling sick, vomiting.
nursing responsibility
Monitor blood glucose levels.
Check for signs of hypoglycemia or lactic acidosis.
Provide patient education about proper medication administration.
Regularly evaluate renal function due to side effects.
Vitamin B12 deficiency, hypoglycemia, renal and hepatic impairment etc. can occur as a result of long-term use so educate the patient about it.
phenothiazine
group
Antipsychotic and
As an anti-anxiety, anti-emetic.
Route
Oral ,IM, IV, Rectal.
Dosage
Adult
Capsule – 30-300mg starting.
Medicine and syrup – 10-25mg starting
injection- 25 to 50 mg
Rectal suppository (suppository)-
50-100mg
pediatric
Capsules- Not given in this form.
medicine and syrup-0.55mg/kg
injection
0.55mg/kg
Rectal suppository (suppository)-
1mg/kg
mode of action
The primary action of phenothiazines as an antipsychotic is by blocking dopamine receptors.
It blocks central and peripheral dopamine receptors.
It also shows antiemetic and anti-anxiety effects.
Indications
Psychotic conditions like schizophrenia, bipolar disease, dementia.
Nausea, vomiting
Agitation, severe hiccups,
For sedation before some surgeries,
Seasonal Sickness,
Post-operative nausea and vomiting,
Severe mental retardation.
Contraindication
Hi Persenctvt,
Bone marrow depression,
Severe central nervous system depression, liver disease.
side effects
Drowsiness, dry mouth,
blurred vision,
constipation,
urinary retention,
involuntary movement,
Changes in BP,
Neuroleptic malignant syndrome.
special precaution
Do not take alcohol with it.
Use with caution in the elderly.
Use with caution even when there is renal, cardio vascular, hepatic impairment.
Use with caution even in a person with a history of seizures.
nursing responsibility